The Science Behind Edibles

Conveniently located to serve the areas of Modesto, Merced, Atwater, Fresno and the Central Valley

Cannabis is now legal in eighteen states, and cannabis-infused edibles are becoming the go-to choice for many consumers. But everyone should understand how the body reacts to cannabis’ natural compounds before they pop a tasty THC treat in their mouth – and especially if it’s their first time. For those of you who have smoked cannabis but never partaken in an edibles experience, be ready to encounter a different type of “high”– one that is less intoxicating but longer-lasting.[1] This difference might be advantageous to those of you who wish for a more sustained experience that doesn’t disrupt their daily or nightly routine. However, as all edible experts can attest, first-timers need to be conscious about not taking too much at once. If it is your first time enjoying edible cannabis, stick to the recommended, if not lower, dosage. Wait a few hours before going back for seconds. 

nclude a wide array of edibles! From tinctures to cookies, we are proud to be Central California’s one-stop-cannabis shop. If you are a returning customer or a first-time shopper, we will be happy to assist you in finding the right product for your occasion. Check out our up-to-date online menu that displays what your nearest dispensary has in stock. You contact us online by clicking here or calling us at (888) 354-0139 if you have any questions.

The Under-Explored Endocannabinoid System

Unlike the other well-researched systems of the body, the endocannabinoid system was discovered fairly recently, in 1988. During research into how the body processes ∆9-THC and cannabidiol (CBD), scientists stumbled upon the endocannabinoid system (ECS) and have raced to investigate its physiological functions. Since the ECS’s discovery and recent cannabis legalization in many states, research into the ECS has exploded within the medical community as scientists and investors rally to figure out how to make the most effective product for the ECS. 

Cannabis Central California

But what exactly is the ECS, and how do THC and CBD interact with it? When observed from a wide-angle lens, the ECS acts as a robust executive system that regulates all of the body’s other systems to continually maintain homeostasis.[2] It’s the conductor of the orchestra; it sets the tempo and volume of the other systems. The ECS bridges the brain to the body with different CB1 and CB2 receptors. In the brain and central nervous system, CB1 receptors send and receive signals in the brain to communicate and react with different changes in the body. On the other hand, there are fewer CB2 receptors in the body and these exist on peripheral nerves in the immune system, so research is still limited on their role.[3] These receptors work in tandem with the other systems of the body to regulate and control temperature, pain, inflammation, hunger, learning, and memory.[4] While scientists and researchers don’t understand all that the ECS does in our bodies, they have found that the ECS acts as a telephone between the brain and body. With the increasing buzz surrounding cannabis research for novel uses, researchers are optimistic that there are still discoveries to be made about this newfound, unsung system. 

How Edibles Are Made

Edibles Central California

After the cannabis plant has been properly harvested, dried, and trimmed, the cannabinoids are ready for extraction. Since cannabinoids are fat-soluble, butter, coconut oil, or avocado oil are routinely used to make edibles. One of the most popular ways to draw out cannabinoids like CBD and THC is by making cannabutter. Cannabutter is often the route many edible companies choose when fine-tuning their cookies, brownies, or pastries. Because it is common in most baked goods, butter is the easiest and most popular choice when baking delicious, sweet treats. First, the cannabis buds need to be decarboxylated. At their original state, cannabis buds carry THCA and CBDA, the precursors to THC and CBD. When cannabis is heated, the thermal effect dispels the oxygen atoms and converts the molecules into active THC and CBD, triggering the therapeutic and psychoactive effects. When smoked through a joint, blunt, or pipe, the active cannabinoids enter the body directly through the lungs. However, to make cannabutter, the buds are baked before being ground up, typically in an oven. This process ensures that the cannabinoids are activated into THC and CBD. Next, the decarboxylated cannabis is steeped in regular butter for a couple of hours before being discarded. After the butter cools, it is potent and ready for use in different baked cannabis edibles.

Two Forms of Delivery

At Medallion, we have many different forms of edibles. From drinks to cookies to tinctures,  there’s a wide range for you to choose from. When choosing what cannabis-infused product is right for you, understand that there are two modes of delivery: ingestion and sublingual. While both offer the same long-lasting benefits, their mechanisms of action vary. 


When consuming cannabis-infused products, the active THC and CBD molecules travel through the digestive tract, interacting with the localized CB1 receptors in the gut. Because the digestive tract is a slow-moving system, cannabinoids are gradually converted into enzymes and absorbed by the gut, which explains why the effects of an edible are long-lasting. As it passes into your liver, THC is metabolized and converted into 11-Hydroxy THC: a different form of THC that provides a psychoactive effect.[5] 11-Hydroxy-THC is more relaxing and long-acting than normal THC, making it ideal for sleep. 


Cannabis can also be taken sublingually in the form of oils, tinctures, or sprays. Under the tongue and around the mouth, there are mucus membranes that quickly absorb cannabinoids. These mucus membranes release these cannabinoids directly into the bloodstream, bypassing the digestive system and liver. While it still isn’t as quick as inhaling the decarboxylated cannabinoids, absorbing cannabinoids sublingually allows for a quicker onset of effects. Taking tinctures, oils, or sprays is a good way to accurately measure out your doses and regulate their effect throughout the day. 

Our Collection of Edibles

Edibles Central California

At Medallion Wellness, we offer our customers the best-tasting and most effective cannabis-infused products on the California market. With our wide range of sweet treats and gummies, we have just the type of experience that interests you.  Choose from energizing sativas, calming indicas, and therapeutic 1:1 CBD to THC edibles. 


Wyld is a Portland, Oregon-based edible company that makes top-shelf gummies for all types of consumers. Committed to using the freshest and highest quality ingredients, Wyld utilizes real fruit in their gummies to give consumers a delicious natural taste. 
  • Huckleberry Hybrid Gummies: made with real fruit and a balanced terpene profile, these gummies promote overall calm well-being. They are perfect for any time of day or night and are a wonderful entry-level gummy for all those trying edibles for the first time. 
  • Marionberry Indica Gummies: after a long day, these natural gummies are perfect to help you unwind. With 10mg of THC per gummy, they are easy to dose for beginners and veterans alike.


Chocolate and cannabis lovers unite! Kiva is an award-winning edible company that has produced deliciously powerful cannabis-infused chocolate bars. With each square equalling 5mg of THC, Kiva makes it easy to divvy up doses. Their chocolate melts in your mouth and their cannabis comes from only the most trusted growers in the industry. No wonder they have been voted the #1 edible brand in the country.

  • CBN Dark Chocolate Midnight Mint: this Kiva bar combines the psychoactive effects of THC with the relaxing waves of CBN. 

Your VIP Experience at Medallion 

At our Central California showrooms and dispensaries, we proudly offer a wide variety of cannabis products. For flower loyalists, we have different indoor and outdoor strains that carry varying levels of THC potency. Also, for those who like to fly under the radar, we have an assortment of vapes to choose from! Go to our online menu, where you can search by brand or strain. If you need help deciding, come on down to one of our six locations where a budtender will help you decide which one of our products is best for you. To learn more about the cannabis industry, check out our other blogs. To learn about our delivery process, head over to our delivery page. If at any time you have questions, don’t hesitate to call us at (888) 354-0139.


  1. Barrus, D. G., Capogrossi, K. L., Cates, S. C., Gourdet, C. K., Peiper, N. C., Novak, S. P., Lefever, T. W., & Wiley, J. L. (2016). Tasty THC: Promises and Challenges of Cannabis Edibles. Methods report (RTI Press), 2016, 10.3768/rtipress.2016.op.0035.1611.
  2. Nazarenus, C. (2020). Medical cannabis handbook for healthcare professionals. Springer Publishing Company.
  3. Mackie K. (2008). Cannabinoid receptors: where they are and what they do. Journal of neuroendocrinology, 20 Suppl 1, 10–14.
  4. Zou, S., & Kumar, U. (2018). Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. International Journal of Molecular Sciences, 19(3), 833. MDPI AG. Retrieved from
  5. Sharma, P., Murthy, P., & Bharath, M. M. (2012). Chemistry, metabolism, and toxicology of cannabis: clinical implications. Iranian journal of psychiatry, 7(4), 149–156.
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